Aortic Aneurysm Rupture in Granulomatosis With Polyangiitis
Aortic Aneurysm Rupture in Granulomatosis With Polyangiitis
Introduction Granulomatosis with polyangiitis is characterized by systemic inflammation of medium and small blood vessels. Aortic involvement in granulomatosis with polyangiitis is extremely rare. As far as we know this is the first reported case of successful treatment in a patient with granulomatosis with polyangiitis complicated with aortic aneurysm rupture.
Case presentation We describe a case of granulomatosis with polyangiitis in a 38-year-old Japanese man who developed an aortic aneurysm rupture 22 years after disease onset. The patient was operated on and a J-graft was inserted. He recovered uneventfully.
Conclusion Recommendations in regard to, and consideration of, aortic involvement should be kept in mind in the long-term careful follow up of granulomatosis with polyangiitis.
Granulomatosis with polyangiitis (GPA) is characterized by a systemic necrotizing vasculitis affecting the small and medium blood vessels. Typically, the upper and lower respiratory tract and often the kidneys are involved. Aortic involvement in GPA is extremely rare, but because of the potential life-threatening risk of rupture it is important to recognize aortic or other large vessel involvement (Table 1). We present a case of GPA in a patient with rupture of a thoracic aortic aneurysm as a complication.
Abstract and Introduction
Abstract
Introduction Granulomatosis with polyangiitis is characterized by systemic inflammation of medium and small blood vessels. Aortic involvement in granulomatosis with polyangiitis is extremely rare. As far as we know this is the first reported case of successful treatment in a patient with granulomatosis with polyangiitis complicated with aortic aneurysm rupture.
Case presentation We describe a case of granulomatosis with polyangiitis in a 38-year-old Japanese man who developed an aortic aneurysm rupture 22 years after disease onset. The patient was operated on and a J-graft was inserted. He recovered uneventfully.
Conclusion Recommendations in regard to, and consideration of, aortic involvement should be kept in mind in the long-term careful follow up of granulomatosis with polyangiitis.
Introduction
Granulomatosis with polyangiitis (GPA) is characterized by a systemic necrotizing vasculitis affecting the small and medium blood vessels. Typically, the upper and lower respiratory tract and often the kidneys are involved. Aortic involvement in GPA is extremely rare, but because of the potential life-threatening risk of rupture it is important to recognize aortic or other large vessel involvement (Table 1). We present a case of GPA in a patient with rupture of a thoracic aortic aneurysm as a complication.
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